Description

(9H-Fluoren-9-Yl)Methoxy]Carbonyl D-Lys(Ac)-Oh CAS NO 320410-22-8 is a protected amino acid derivative, specifically an Nα-Fmoc and Nε-acetyl protected D-lysine, which serves as a critical building block in solid-phase peptide synthesis (SPPS). Its primary value lies in enabling the controlled, sequential assembly of complex peptides, particularly those requiring the incorporation of the D-isomer of lysine for enhanced metabolic stability or specific conformational properties. This high-purity intermediate is essential for researchers and manufacturers in pharmaceutical development, biotechnology, and advanced life science research focused on novel peptide therapeutics, diagnostics, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid for the automated synthesis of custom peptides.
• Pharmaceutical R&D: Building block for the development of peptide-based drugs, including antimicrobial peptides (AMPs) and hormone analogs.
• Peptide Library Construction: Used in combinatorial chemistry to create diverse peptide libraries for drug discovery and screening.
• Bioconjugation: The acetyl-protected side chain allows for selective deprotection and subsequent conjugation with labels, tags, or other molecules.
• Structural Biology Studies: Incorporation of D-amino acids like D-lysine to study peptide folding, stability, and receptor interactions.
• Production of Specialty Peptides: Manufacture of peptides for research reagents, diagnostic kits, and cosmetic active ingredients.

Basic Information

Product Name	(9H-Fluoren-9-Yl)Methoxy]Carbonyl D-Lys(Ac)-Oh
CAS No.	320410-22-8
Molecular Formula	C23H26N2O5
Molecular Weight	410.46 g/mol
Synonyms	Fmoc-D-Lys(Ac)-OH; Nα-Fmoc-Nε-acetyl-D-lysine; Fmoc-D-Lysine(Nε-acetyl)-OH; (9-Fluorenylmethoxycarbonyl)-Nε-acetyl-D-lysine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N6-acetyl-D-lysine; Fmoc-D-Lys(Acetyl)-OH; D-Lysine, N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N6-acetyl-
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-Yl)Methoxy]Carbonyl D-Lys(Ac)-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm the D-configuration, ensuring it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) with detailed specifications for identity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.