Description

Ac-Val-Tyr-Leu-Lys-Ala-Sbzl is a synthetic peptide derivative, specifically a modified peptide sequence with a C-terminal benzyl ester (Sbzl) protecting group. This compound is a crucial building block and intermediate in advanced peptide synthesis and pharmaceutical research, enabling the controlled construction of complex bioactive molecules. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers focused on peptide-based drug discovery, proteomics, and biochemical studies.

Application

• Pharmaceutical Intermediate: Serves as a key protected fragment in the solid-phase and solution-phase synthesis of therapeutic peptides and peptidomimetics.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate protease activity and specificity.
• Drug Discovery: Acts as a core scaffold for structure-activity relationship (SAR) studies to optimize peptide drug candidates for enhanced stability and efficacy.
• Proteomics & Diagnostics: Employed in the development of affinity ligands, standards, and reagents for mass spectrometry and diagnostic assays.
• Academic Research: Utilized in university and institutional labs for teaching and investigating peptide chemistry, protecting group strategies, and molecular biology.

Basic Information

Product Name	Ac-Val-Tyr-Leu-Lys-Ala-Sbzl
CAS No.	320349-22-2
Molecular Formula	C41H61N7O9
Molecular Weight	795.97 g/mol
Synonyms	Ac-Val-Tyr-Leu-Lys-Ala-OBzl; N-Acetyl-L-valyl-L-tyrosyl-L-leucyl-L-lysyl-L-alanine benzyl ester; Ac-VYLKA-OBzl; Ac-Val-Tyr-Leu-Lys-Ala benzyl ester; L-Alanine, N-acetyl-L-valyl-L-tyrosyl-L-leucyl-L-lysyl-, benzyl ester; Benzyl N-acetyl-L-valyl-L-tyrosyl-L-leucyl-L-lysyl-L-alaninate; 320349-22-2
EINECS	Contact for details

Quality Control

Our Ac-Val-Tyr-Leu-Lys-Ala-Sbzl is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines for the manufacture of non-compendial research chemicals, ensuring traceability and reliable supply for critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.