Description

H-Thr-Phe-Arg-Gly-Ala-Pro-Oh is a synthetic heptapeptide sequence with the CAS number 320347-28-2. This compound is of significant interest in biochemical and pharmaceutical research due to its specific amino acid arrangement, which can mimic bioactive regions of larger proteins. It serves as a critical intermediate or reference standard for researchers and manufacturers in the life sciences sector. Target industries include peptide synthesis, pharmaceutical development, and academic research institutions.

Application

• Pharmaceutical Research & Development: Used as a key intermediate in the synthesis of novel therapeutic peptides or peptidomimetics.
• Biochemical Standard: Serves as a high-purity reference standard for analytical method development and validation in quality control laboratories.
• Proteomics & Enzymology Studies: Employed as a substrate or model peptide to study enzyme kinetics, specificity, and protein-peptide interactions.
• Cosmeceutical Formulations: Investigated for potential bioactive properties in advanced skincare and cosmetic products.
• Academic & Institutional Research: A fundamental tool for university labs and research institutes studying peptide chemistry, structure-activity relationships, and molecular biology.

Basic Information

Product Name	H-Thr-Phe-Arg-Gly-Ala-Pro-Oh
CAS No.	320347-28-2
Molecular Formula	C32H50N10O9
Molecular Weight	718.81 g/mol
Synonyms	Threonyl-Phenylalanyl-Arginyl-Glycyl-Alanyl-Proline; H-Thr-Phe-Arg-Gly-Ala-Pro-OH; Thr-Phe-Arg-Gly-Ala-Pro; TFRGAP Peptide; Heptapeptide TFRGAP; L-Threonyl-L-phenylalanyl-L-arginylglycyl-L-alanyl-L-proline; Acetyl TFRGAP (related derivative); CAS 320347-28-2
EINECS	Contact for details

Quality Control

Our H-Thr-Phe-Arg-Gly-Ala-Pro-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide Certificates of Analysis (COA) with detailed results for traceability and compliance. Specifications can meet the requirements for research-grade and cGMP-grade materials upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere such as argon or nitrogen. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay (by AAA)	≥ 97.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Bacterial Endotoxins	< 10 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.