Description

Pyr-His-Trp-Ser-Tyr-D-Trp-Leu-Ser-Pro-Nhet CAS NO 319432-01-4 is a synthetic decapeptide amide, a structural analog of growth hormone-releasing peptide-6 (GHRP-6). This compound is significant for its role in research focused on growth hormone secretagogues and their receptors. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in endocrinology, metabolic disorder studies, and peptide-based therapeutic development.

Application

• Pharmaceutical Research & Development: As a key reference standard and active investigational compound in studies of growth hormone secretagogue receptor (GHSR) activity.
• Endocrinology Studies: For in vitro and in vivo research into the mechanisms of growth hormone release and regulation.
• Metabolic Disorder Research: Investigation of potential therapeutic applications for conditions related to growth hormone deficiency.
• Biochemical Assay Development: Used as a ligand in receptor binding assays and functional cell-based assays to screen for GHSR agonists or antagonists.
• Peptide Chemistry & Analog Synthesis: Serves as a core structure for the design and synthesis of novel peptide analogs with modified biological activity.
• Academic & Preclinical Studies: Fundamental research tool in university and institutional labs studying the ghrelin pathway and its physiological effects.

Basic Information

Product Name	Pyr-His-Trp-Ser-Tyr-D-Trp-Leu-Ser-Pro-Nhet
CAS No.	319432-01-4
Molecular Formula	C61H78N16O13
Molecular Weight	1227.4 g/mol
Synonyms	GHRP-6 Amide; Growth Hormone Releasing Peptide-6 (Amide); P-H-W-S-Y-(D-W)-L-S-P-NH2; His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 analog; GHRP-6 (1-6) extended analog; L-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-tryptophyl-L-leucyl-L-seryl-L-prolinamide; GHS Receptor Ligand; Ghrelin Mimetic Peptide
EINECS	Contact for details

Quality Control

Our Pyr-His-Trp-Ser-Tyr-D-Trp-Leu-Ser-Pro-Nhet is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing purity, content, and analytical results. The product is suitable for research use under GLP (Good Laboratory Practice) guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC-MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay (Peptide Content)	≥ 80.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 8.0%
Acetate Content (HPLC)	≤ 15.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.