Description

2'-(Trifluoromethyl)[1,1'-Biphenyl]-4-Ol is a high-purity, functionalized biphenyl derivative characterized by a phenolic hydroxyl group and a trifluoromethyl substituent. This compound serves as a versatile and critical advanced pharmaceutical intermediate (API) and a key building block in modern synthetic chemistry. It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used as a building block for novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core structure in the synthesis of advanced electronic materials for displays and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into polymer chains to impart specific properties like thermal stability, chemical resistance, or unique optical characteristics.
• Ligand & Catalyst Development: Utilized in organometallic chemistry to create novel ligands for catalytic systems in asymmetric synthesis.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	2'-(Trifluoromethyl)[1,1'-Biphenyl]-4-Ol
CAS No.	319014-58-9
Molecular Formula	C₁₃H₉F₃O
Molecular Weight	238.21 g/mol
Synonyms	[1,1'-Biphenyl]-4-ol, 2'-(trifluoromethyl)-; 2'-(Trifluoromethyl)-[1,1'-biphenyl]-4-ol; 4-Hydroxy-2'-(trifluoromethyl)biphenyl; 2-(Trifluoromethyl)biphenyl-4-ol; 4'-Hydroxy-2-trifluoromethylbiphenyl; 2-Trifluoromethyl-4-hydroxybiphenyl; Biphenyl-4-ol, 2'-trifluoromethyl-
EINECS	Contact for details

Quality Control

Our 2'-(Trifluoromethyl)[1,1'-Biphenyl]-4-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent lot-to-lot performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.