Description

Adrenomedullin (16-31) (Human, Pig) is a specific bioactive peptide fragment derived from the full-length adrenomedullin hormone. This compound is of significant interest for research into cardiovascular regulation, tumor biology, and inflammatory processes due to its potent vasodilatory and cytoprotective properties. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on peptide therapeutics and diagnostic assay development.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating cardiovascular function, blood pressure regulation, and endothelial cell activity.
• Pharmacological Assay Development: Serves as a critical ligand in receptor binding studies and functional assays to screen for adrenomedullin receptor agonists or antagonists.
• Peptide Chemistry & Drug Discovery: Acts as a key intermediate or template for the synthesis of novel peptide analogs with potential therapeutic applications.
• Diagnostic Kit Manufacturing: Employed in the production of immunoassay kits (e.g., ELISA) for the quantitative measurement of adrenomedullin-related peptides in biological samples.
• Cell Culture & In Vitro Studies: Applied in cell-based models to study its effects on cell proliferation, apoptosis, and angiogenesis in cancer and cardiovascular research.

Basic Information

Item	Detail
Product Name	Adrenomedullin (16-31) (Human, Pig)
CAS No.	318480-38-5
Molecular Formula	C78H122N24O21
Molecular Weight	1731.96 g/mol
Synonyms	ADM (16-31); Adrenomedullin fragment 16-31; Human, Porcine Adrenomedullin (16-31); H-Arg-Tyr-Ile-Gln-Ser-Phe-Gln-Gly-Leu-Nle-Ser-His-Gln-Asp-Lys-Asp-NH2; AM (16-31); ADM-16; Preproadrenomedullin N-terminal 20 peptide (PAMP) related fragment
EINECS	Contact for details

Quality Control

Our Adrenomedullin (16-31) (Human, Pig) is produced under stringent conditions to ensure high purity and batch-to-batch consistency, critical for reliable research outcomes. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, MS for identity confirmation, and amino acid analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive) and easily oxidized; it is recommended to store under an inert atmosphere when the container is opened frequently. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	± 10% of theoretical
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.