Description

2-(Prop-2-Ynylsulfanyl)-5,6,7,8-Tetrahydro[1]Benzothieno[2,3-D]Pyrimidin-4-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel, biologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of targeted kinase inhibitors and other small-molecule drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Employed in biochemical assays to study specific enzyme interactions and cellular pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Utilized in university laboratories for fundamental research on heterocyclic chemistry and its biological applications.

Basic Information

Product Name	2-(Prop-2-Ynylsulfanyl)-5,6,7,8-Tetrahydro[1]Benzothieno[2,3-D]Pyrimidin-4-Amine
CAS No.	315695-07-9
Molecular Formula	C13H13N3S2
Molecular Weight	275.39 g/mol
Synonyms	4-Amino-2-(prop-2-yn-1-ylthio)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine; 2-(Prop-2-yn-1-ylthio)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine; 2-(Prop-2-ynylsulfanyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-amine; CAS 315695-07-9; Tetrahydrobenzothienopyrimidine amine derivative; Propargylthio-tetrahydrobenzothienopyrimidine
EINECS	Contact for details

Quality Control

Our 2-(Prop-2-Ynylsulfanyl)-5,6,7,8-Tetrahydro[1]Benzothieno[2,3-D]Pyrimidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research-grade and pharmaceutical intermediate standards. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.