Description

4-((2-Fluorobenzyl)Thio)-5,6,7,8-Tetrahydrobenzo[4,5]Thieno[2,3-D]Pyrimidine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel therapeutic agents. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of small-molecule drugs, particularly those targeting kinase inhibition and other specialized biological pathways.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates for oncology, neurology, and inflammatory diseases.
• Kinase Inhibitor Research: Used in the discovery and development of novel kinase inhibitors due to its privileged pyrimidine-thiophene scaffold.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying enzyme function and cellular signaling pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom API synthesis projects.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and medicinal chemistry programs.

Basic Information

Product Name	4-((2-Fluorobenzyl)Thio)-5,6,7,8-Tetrahydrobenzo[4,5]Thieno[2,3-D]Pyrimidine
CAS No.	315682-85-0
Molecular Formula	C19H17FN2S2
Molecular Weight	356.48 g/mol
Synonyms	4-[(2-Fluorophenyl)methyl]sulfanyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine; 4-(2-Fluorobenzylthio)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine; Benzo[4,5]thieno[2,3-d]pyrimidine, 4-((2-fluorobenzyl)thio)-5,6,7,8-tetrahydro-; 315682-85-0; 4-(2-Fluorobenzylsulfanyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 4-((2-Fluorobenzyl)Thio)-5,6,7,8-Tetrahydrobenzo[4,5]Thieno[2,3-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This material is light-sensitive and easily oxidized; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.