Description

2-((4-Oxo-3,4,5,6,7,8-Hexahydrobenzo[4,5]Thieno[2,3-D]Pyrimidin-2-Yl)Thio)-n-(Pyridin-3-Ylmethyl)Acetamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its role as a critical building block in the synthesis of novel, targeted therapeutic agents, particularly in oncology and other disease areas. Research institutions and pharmaceutical manufacturers engaged in drug discovery and development require this precise chemical entity to explore new biological pathways and create next-generation medications.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel small-molecule drug candidates targeting specific enzymes or receptors.
• Oncology Research: Used in the development of potential kinase inhibitors and other anti-cancer agents due to its fused thienopyrimidine core.
• Chemical Biology: Employed as a molecular probe or scaffold for studying protein-ligand interactions and cellular signaling pathways.
• Medicinal Chemistry R&D: A vital starting material for structure-activity relationship (SAR) studies and lead optimization programs in drug discovery.
• Custom Synthesis: Provided to contract research and manufacturing organizations (CROs/CMOs) for client-specific synthesis projects.
• Reference Standard: Supplied as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	2-((4-Oxo-3,4,5,6,7,8-Hexahydrobenzo[4,5]Thieno[2,3-D]Pyrimidin-2-Yl)Thio)-n-(Pyridin-3-Ylmethyl)Acetamide
CAS No.	315239-11-3
Molecular Formula	C19H20N4O2S2
Molecular Weight	400.52 g/mol
Synonyms	2-({[4-Oxo-3,4,5,6,7,8-hexahydro-1-benzothieno[2,3-d]pyrimidin-2-yl]sulfanyl})-N-(pyridin-3-ylmethyl)acetamide; N-(Pyridin-3-ylmethyl)-2-((4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamide; 2-((4-Oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)-N-(3-pyridylmethyl)acetamide; CAS 315239-11-3
EINECS	Contact for details

Quality Control

Our 2-((4-Oxo-3,4,5,6,7,8-Hexahydrobenzo[4,5]Thieno[2,3-D]Pyrimidin-2-Yl)Thio)-n-(Pyridin-3-Ylmethyl)Acetamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to ICH guidelines for stability and impurity characterization, providing the traceability and documentation required for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.