Description

Bz-Gly-Lys-Val-Oh CAS NO 315229-41-5 is a protected tetrapeptide derivative, specifically a benzoyl-glycyl-lysyl-valine sequence. This compound serves as a crucial building block in solid-phase peptide synthesis (SPPS), enabling the controlled construction of complex peptides and proteins for research and development. It is primarily utilized by pharmaceutical researchers, biotech companies, and academic institutions engaged in peptide-based drug discovery, proteomics, and biochemical studies.

Application

• Peptide Synthesis Intermediate: A key protected fragment for the stepwise assembly of longer, biologically active peptide sequences in both research and process development.
• Pharmaceutical R&D: Used in the discovery and development of novel therapeutic peptides targeting various diseases, including metabolic disorders and cancers.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies to investigate protease specificity and function.
• Proteomics & Structural Biology: Serves as a standard or reference compound in mass spectrometry and chromatography for peptide analysis and characterization.
• Custom Peptide Production: A fundamental raw material for contract manufacturing organizations (CMOs) producing custom peptides for clients.

Basic Information

Product Name	Bz-Gly-Lys-Val-Oh
CAS No.	315229-41-5
Molecular Formula	C22H34N4O6
Molecular Weight	450.53 g/mol
Synonyms	Benzoyl-Glycyl-Lysyl-Valine; Bz-Gly-Lys-Val-OH; Nα-Benzoylglycyl-Nε-protected-lysylvaline; Glycine, N-[N2-(N-benzoylglycyl)-N6-(tert-butoxycarbonyl)-L-lysyl]-L-valine-; (S)-2-((S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)hexanamido)-3-methylbutanoic acid (related Fmoc variant); Bzl-Gly-Lys(Boc)-Val-OH; Tetrapeptide Bz-Gly-Lys(Boc)-Val-OH; 315229-41-5
EINECS	Contact for details

Quality Control

Our Bz-Gly-Lys-Val-Oh is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting compliance with agreed specifications. Our quality commitment supports applications in GMP and cGMP environments where traceability and documentation are paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.