Description

(Ala31,Aib32)-Neuropeptide Y (Porcine) is a synthetic analog of the endogenous neuropeptide Y (NPY), engineered with specific amino acid substitutions to enhance its stability and biological activity. This modified peptide is a critical research tool for studying the NPY receptor system, which plays a pivotal role in regulating energy balance, cardiovascular function, and stress responses. It is essential for pharmaceutical R&D, academic research, and diagnostic development focused on metabolic disorders, obesity, and cardiovascular diseases.

Application

• Pharmacological Research: Used as a stable, potent agonist for in vitro and in vivo studies of Y1, Y2, Y4, and Y5 receptor subtypes.
• Drug Discovery & Development: Serves as a reference standard and lead compound for developing novel therapeutics targeting appetite regulation and metabolic syndromes.
• Biochemical Assays: Employed in receptor binding studies, signal transduction pathway analysis, and functional cellular assays.
• Academic & Institutional Research: A key reagent for investigating the physiological and pathophysiological roles of NPY in the central and peripheral nervous systems.
• Diagnostic Development: Potential use in the development of immunoassays and other diagnostic tools for conditions related to NPY dysregulation.

Basic Information

Product Name	(Ala31,Aib32)-Neuropeptide Y (Porcine)
CAS No.	313988-59-9
Molecular Formula	C190H288N58O57S2
Molecular Weight	4253.8 g/mol
Synonyms	[Ala31, Aib32]-NPY; NPY (porcine) [Ala31, Aib32] analog; Neuropeptide Y (porcine) (Ala31, Aib32)-substituted; hNPY (Ala31, Aib32); Aib32-NPY; NPY analog; NPY receptor agonist; NPY (22-36), [Ala31, Aib32]-
EINECS	Contact for details

Quality Control

Every batch of (Ala31,Aib32)-Neuropeptide Y (Porcine) is manufactured under strict quality systems and undergoes comprehensive analytical testing to ensure identity, purity, and biological activity. Our products are characterized using advanced techniques including HPLC, MS, and amino acid analysis. A Certificate of Analysis (COA) detailing purity, peptide content, and analytical data is provided with each shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, consider aliquoting to avoid repeated freeze-thaw cycles. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by amino acid analysis)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Biological Activity	Determined by functional assay (e.g., cAMP inhibition)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.