Description

Methyl 4-Hydroxyquinazoline-7-Carboxylate is a high-purity, functionalized quinazoline derivative serving as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, providing both a carboxylate ester and a hydroxyl group on the quinazoline core, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of targeted kinase inhibitors and other biologically active quinazoline-based drug candidates.
• Agrochemical Research: Used as a scaffold for developing new herbicides, fungicides, and plant growth regulators with specific modes of action.
• Organic Synthesis Building Block: Serves as a versatile starting material for constructing complex polyheterocyclic systems and fine chemicals.
• Material Science Research: Potential monomer or functional additive in the development of specialty polymers and advanced organic electronic materials.
• Chemical Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Methyl 4-Hydroxyquinazoline-7-Carboxylate
CAS No.	313535-84-1
Molecular Formula	C10H8N2O3
Molecular Weight	204.18 g/mol
Synonyms	Methyl 7-carboxy-4-hydroxyquinazoline; 4-Hydroxyquinazoline-7-carboxylic acid methyl ester; 7-(Methoxycarbonyl)-4-quinazolinol; Methyl 4-oxo-1,4-dihydroquinazoline-7-carboxylate; 4-Quinazolinol, 7-(methoxycarbonyl)-; 1,4-Dihydro-4-oxoquinazoline-7-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-Hydroxyquinazoline-7-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.