Description

4-(5,6,7,8-Tetrahydro-Benzo[4,5]Thieno[2,3-D]Pyrimidin-4-Ylamino)-Butyric Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly for its role as a key building block in synthesizing novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers focused on developing kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly in oncology and inflammatory disease research.
• Kinase Inhibitor Development: Used as a core scaffold or a key fragment in the design and synthesis of potent and selective kinase inhibitors.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize drug-like properties and biological activity.
• Biochemical Tool Compound: Utilized in biochemical assays and high-throughput screening to identify and validate new therapeutic targets.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects for clients.
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	4-(5,6,7,8-Tetrahydro-Benzo[4,5]Thieno[2,3-D]Pyrimidin-4-Ylamino)-Butyric Acid
CAS No.	313534-23-5
Molecular Formula	C₁₆H₁₉N₃O₂S
Molecular Weight	317.41 g/mol
Synonyms	4-[(5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-yl)amino]butanoic acid; 4-(5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-ylamino)butyric acid; 4-[(5,6,7,8-Tetrahydro-4H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-yl)amino]butanoic acid; CAS 313534-23-5; Butanoic acid, 4-[(5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-yl)amino]-; 4-(5,6,7,8-Tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-ylamino)-butyric acid
EINECS	Contact for details

Quality Control

Our 4-(5,6,7,8-Tetrahydro-Benzo[4,5]Thieno[2,3-D]Pyrimidin-4-Ylamino)-Butyric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.