Description

7-(4-Chlorobenzyl)-3-Methyl-8-(4-Methylpiperazin-1-Yl)-3,7-Dihydro-1H-Purine-2,6-Dione is a high-purity, advanced pharmaceutical intermediate belonging to the purine-dione class of heterocyclic compounds. This compound matters for its role as a critical building block in the synthesis of novel, targeted therapeutic agents, offering researchers and manufacturers a reliable and well-characterized starting material. It is primarily needed by pharmaceutical R&D teams and fine chemical producers engaged in developing new drug candidates, particularly in oncology and neurology.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Kinase Inhibitor Research: Used in the synthesis of potential purine-based kinase inhibitors for targeted cancer therapies.
• Neurological Drug Discovery: Employed as a scaffold in medicinal chemistry programs focused on central nervous system (CNS) disorders.
• Biochemical Research: Acts as a reference standard or tool compound in biochemical assays and pharmacological studies.
• Custom Synthesis: Provides a versatile starting point for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.

Basic Information

Product Name	7-(4-Chlorobenzyl)-3-Methyl-8-(4-Methylpiperazin-1-Yl)-3,7-Dihydro-1H-Purine-2,6-Dione
CAS No.	313471-55-5
Molecular Formula	C18H21ClN6O2
Molecular Weight	388.85 g/mol
Synonyms	7-[(4-Chlorophenyl)methyl]-3-methyl-8-(4-methyl-1-piperazinyl)-3,7-dihydro-1H-purine-2,6-dione; 8-(4-Methylpiperazin-1-yl)-7-(4-chlorobenzyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione; 313471-55-5; Purine-2,6-dione, 7-[(4-chlorophenyl)methyl]-3-methyl-8-(4-methyl-1-piperazinyl)-3,7-dihydro-1H-; 7-(4-Chlorobenzyl)-3-methyl-8-(4-methylpiperazin-1-yl)-1H-purine-2,6(3H,7H)-dione
EINECS	Contact for details

Quality Control

Our 7-(4-Chlorobenzyl)-3-Methyl-8-(4-Methylpiperazin-1-Yl)-3,7-Dihydro-1H-Purine-2,6-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this moisture-sensitive compound from humidity. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.