Description

Ethyl 5-(4-Bromophenyl)-7-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound matters because it integrates a bromophenyl group and a trifluoromethyl group on a pyrazolopyrimidine core, offering versatile reactivity and unique physicochemical properties for creating novel molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in drug discovery, material science, and the development of specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other biologically active molecules targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel active ingredients for crop protection, leveraging the stability and bioactivity conferred by the trifluoromethyl and bromine substituents.
• Material Science Building Block: Employed in the creation of advanced organic materials, such as organic light-emitting diodes (OLEDs) or conductive polymers, due to its conjugated heterocyclic system.
• Chemical Biology Probe: Acts as a scaffold for developing molecular probes to study enzyme function and cellular pathways in academic and industrial research settings.
• Custom Synthesis & Contract Manufacturing: A key starting material for fine chemical manufacturers offering bespoke synthesis services to clients in life sciences.

Basic Information

Product Name	Ethyl 5-(4-Bromophenyl)-7-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS No.	313249-39-7
Molecular Formula	C16H11BrF3N3O2
Molecular Weight	414.18 g/mol
Synonyms	Ethyl 5-(p-bromophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate; 5-(4-Bromophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid ethyl ester; 313249-39-7; SCHEMBL21805527; BCP31133; ZINC000253899793; AKOS025147064; Ethyl 5-(4'-bromophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 5-(4-Bromophenyl)-7-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports your research and development needs with reliable, high-purity building blocks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.