Description

Gm-Csf (17-31) is a synthetic peptide fragment derived from the Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) protein. This compound is a critical research tool for studying immune cell signaling, differentiation, and proliferation mechanisms. It is primarily utilized by biotechnology and pharmaceutical R&D laboratories focused on immunology, hematopoiesis, and therapeutic peptide development.

Application

• Biomedical Research: Used as a reference standard or active agent in studies of granulocyte and macrophage biology, immune response modulation, and cytokine signaling pathways.
• Drug Discovery: Serves as a key intermediate or lead compound in the development of immunomodulatory therapies and cytokine-based pharmaceuticals.
• Diagnostic Development: Employed in the design and calibration of immunoassays (e.g., ELISA) to detect GM-CSF activity or autoantibodies in clinical samples.
• Cell Culture & Differentiation: Applied in *in vitro* cell culture systems to stimulate the growth and differentiation of hematopoietic progenitor cells into granulocytes and macrophages.
• Structure-Activity Relationship (SAR) Studies: Essential for mapping the bioactive regions of the full-length GM-CSF protein to understand receptor binding and function.
• Antigen Production: Can be used to generate antibodies specific to regions of the GM-CSF molecule for research and diagnostic purposes.

Basic Information

Product Name	Gm-Csf (17-31)
CAS No.	313219-94-2
Molecular Formula	C78H124N22O23S
Molecular Weight	1746.0 g/mol
Synonyms	GM-CSF (17-31); Granulocyte-Macrophage Colony-Stimulating Factor (17-31); GMCSF (17-31); Sargramostim (17-31); Molgramostim (17-31); CSF2 (17-31); Colony Stimulating Factor 2 (17-31); H-Leu-Glu-Lys-Leu-Lys-Leu-Pro-Ser-Ser-Asp-Phe-Pro-Met-Pro-Val-Asn-OH
EINECS	Contact for details

Quality Control

Our Gm-Csf (17-31) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets exacting research-grade specifications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.