Description

Dl-Lysine-6-13C-ε-15N Dihydro-Chloride is a high-purity, stable isotope-labeled derivative of the essential amino acid lysine, specifically designed for advanced research and analytical applications. This compound is critical for precise metabolic pathway tracing, protein turnover studies, and quantitative mass spectrometry, offering unmatched accuracy in scientific investigations. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic manufacturers engaged in proteomics, metabolomics, and stable isotope labeling by amino acids in cell culture (SILAC) workflows.

Application

• Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC): For quantitative proteomics to measure differential protein expression in cell cultures.
• Metabolic Flux Analysis (MFA): As a tracer to study central carbon metabolism and amino acid biosynthesis pathways in biological systems.
• Mass Spectrometry Internal Standards: For the accurate quantification of lysine and lysine-containing peptides/proteins using LC-MS/MS and GC-MS techniques.
• Pharmacokinetic and Drug Metabolism Studies: To track the absorption, distribution, metabolism, and excretion (ADME) of novel therapeutic compounds.
• Nutritional Research: Investigating protein metabolism, amino acid requirements, and turnover rates in vivo.
• Diagnostic Assay Development: As a critical component in calibrators and controls for clinical mass spectrometry assays.

Basic Information

Product Name	Dl-Lysine-6-13C-ε-15N Dihydro-Chloride
CAS No.	312623-81-7
Molecular Formula	C613CH1415N2O2 • 2HCl
Molecular Weight	Contact for details
Synonyms	(6-13C,ε-15N)-DL-Lysine dihydrochloride; DL-Lysine-6-13C,ε-15N dihydrochloride; 2,6-Diaminohexanoic-6-13C,6-15N acid dihydrochloride; (RS)-2,6-Diaminocaproic-6-13C,6-15N acid hydrochloride; 13C,15N-Labeled DL-Lysine 2HCl; Isotopically labeled DL-lysine dihydrochloride; Lysine-13C,15N dihydrochloride (racemic)
EINECS	Contact for details

Quality Control

Every batch of Dl-Lysine-6-13C-ε-15N Dihydro-Chloride is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure high chemical purity, isotopic enrichment, and radiochemical purity as required for sensitive research applications. Certificates of Analysis (COA) detailing lot-specific results for assay, isotopic purity, and impurities are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability. For long-term storage, consider storing under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Enrichment (6-13C)	≥ 99 atom % 13C
Isotopic Enrichment (ε-15N)	≥ 99 atom % 15N
Chemical Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.