Description

Benzeneethanamine, 2,3-Difluoro- (9Ci) CAS NO 311346-59-5 is a specialized fluorinated aromatic amine building block of significant interest in advanced organic synthesis. Its core value lies in the strategic incorporation of fluorine atoms and a primary amine functional group, enabling precise modification of molecular properties for high-value applications. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for creating novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides, where fluorine atoms improve lipophilicity and environmental stability.
• Liquid Crystal & Electronic Materials: Serves as a precursor for fluorinated diamines used in polyimide resins and liquid crystal displays (LCDs), offering excellent thermal and chemical resistance.
• Advanced Polymer Chemistry: Employed as a monomer or chain modifier in the production of high-performance, specialty polymers with tailored properties.
• Organic Synthesis Reagent: Acts as a versatile reactant for introducing the 2,3-difluorophenethylamine moiety into more complex molecular architectures via amide formation or reductive amination.
• Chemical Research & Development: A valuable tool for medicinal and process chemists exploring structure-activity relationships (SAR) and novel synthetic pathways.

Basic Information

Product Name	Benzeneethanamine, 2,3-Difluoro- (9Ci)
CAS No.	311346-59-5
Molecular Formula	C8H9F2N
Molecular Weight	157.16 g/mol
Synonyms	2,3-Difluorophenethylamine; 2-(2,3-Difluorophenyl)ethan-1-amine; 1-(2,3-Difluorophenyl)-2-aminoethane; 2,3-Difluoro-β-phenylethylamine; 2,3-DFPEA; (2,3-Difluorophenyl)ethylamine; β-(2,3-Difluorophenyl)ethylamine
EINECS	Contact for details

Quality Control

Every batch of Benzeneethanamine, 2,3-Difluoro- is produced and tested under strict quality management protocols to ensure consistency and purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support cGMP compliance for pharmaceutical intermediate use, and we can accommodate custom purity specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Specific Gravity	~1.15 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.