Description

5-(4-Fluorophenyl)-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid CAS NO 310451-83-3 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical manufacturers and R&D laboratories engaged in developing targeted therapies, where its specific molecular architecture serves as a key building block.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used extensively in R&D for structure-activity relationship (SAR) studies and lead optimization processes.
• API Synthesis: Serves as a precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) targeting specific biological pathways.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard for analytical method development and validation.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.

Basic Information

Product Name	5-(4-Fluorophenyl)-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid
CAS No.	310451-83-3
Molecular Formula	C14H7F4N3O2
Molecular Weight	325.22 g/mol
Synonyms	5-(4-Fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid; 5-(p-Fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid; 310451-83-3; Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, 5-(4-fluorophenyl)-7-(trifluoromethyl)-; 5-(4-Fluorophenyl)-7-(trifluoromethyl)-1H-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(4-Fluorophenyl)-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere or with desiccant for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.