Description

2-(Tetrahydro-Furan-2-Ylmethoxy)-5-Trifluoromethyl-Phenylamine is a specialized aromatic amine derivative featuring a tetrahydrofuran-linked methoxy group and a trifluoromethyl substituent, making it a valuable fluorinated building block. This compound is critical for research and development in advanced organic synthesis, where its unique structure enables the introduction of specific functional groups and fluorine atoms. It is primarily sought after by pharmaceutical, agrochemical, and advanced material scientists for the development of novel active ingredients and high-performance polymers.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and synthesis of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Development: Used in creating novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to develop specialty polymers with tailored thermal, chemical, or surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination, to construct complex molecular architectures.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for exploring new synthetic methodologies and fluorine chemistry.

Basic Information

Product Name	2-(Tetrahydro-Furan-2-Ylmethoxy)-5-Trifluoromethyl-Phenylamine
CAS No.	309282-21-1
Molecular Formula	C₁₂H₁₄F₃NO₂
Molecular Weight	261.24 g/mol
Synonyms	5-(Trifluoromethyl)-2-[(tetrahydro-2-furanyl)methoxy]benzenamine; 2-[(Tetrahydrofuran-2-yl)methoxy]-5-(trifluoromethyl)aniline; 2-[(Oxolan-2-yl)methoxy]-5-(trifluoromethyl)aniline; 2-(Tetrahydrofuran-2-ylmethoxy)-5-trifluoromethylphenylamine; 2-(Tetrahydro-2-furanylmethoxy)-5-(trifluoromethyl)benzenamine; 5-Trifluoromethyl-2-(tetrahydrofurfuryloxy)aniline; 309282-21-1; Benzenamine, 2-[(tetrahydro-2-furanyl)methoxy]-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-(Tetrahydro-Furan-2-Ylmethoxy)-5-Trifluoromethyl-Phenylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.