Description

H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-Oh (Cys3-Cys9) is a synthetic cyclic peptide featuring a disulfide bridge between cysteine residues at positions 3 and 9, which is critical for its structural stability and biological activity. This compound is a valuable research-grade biochemical for studying peptide conformation, receptor-ligand interactions, and as a potential precursor in pharmaceutical development. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in peptide-based drug discovery and biochemical analysis.

Application

• Biochemical Research: Used as a model compound for studying the structure-activity relationships (SAR) of cyclic peptides and disulfide bond formation.
• Pharmaceutical R&D: Serves as a key intermediate or reference standard in the development of novel peptide therapeutics targeting specific biological pathways.
• Enzyme/Receptor Studies: Employed in assays to investigate enzyme inhibition, receptor binding affinity, and signal transduction mechanisms.
• Academic Research: A critical tool in university and institutional labs for teaching and advanced research in peptide chemistry and molecular biology.
• Standards & Calibration: Acts as a high-purity analytical standard for method development and quality control in peptide synthesis and analysis.

Basic Information

Product Name	H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-Oh (Cys3-Cys9)
CAS No.	309247-84-5
Molecular Formula	C44H58N10O12S2
Molecular Weight	983.12 g/mol
Synonyms	Cyclo(Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys); Cys3-Cys9 Cyclic Peptide; Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys Cyclic Disulfide; Cyclic Nonapeptide (Cys3, Cys9); H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-OH (cyclic); 309247-84-5; Cyclo(PFCNAFTGC)
EINECS	Contact for details

Quality Control

Our H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-Oh (Cys3-Cys9) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Disulfide Bond Integrity (Assay)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.