Description

(Tyr0)-Kaliuretic Peptide (Human) CAS NO 309245-24-7 is a synthetic peptide analog of human kaliuretic peptide, a hormone involved in renal sodium and potassium excretion. This high-purity compound is a critical research tool for investigating cardiovascular and renal physiology, particularly mechanisms related to blood pressure regulation and electrolyte balance. It is essential for pharmaceutical R&D teams, academic researchers, and diagnostic developers focused on hypertension, heart failure, and novel therapeutic pathways.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of natriuretic and kaliuretic peptide receptors (NPRs).
• Cardiovascular Pharmacology: Investigation of mechanisms for blood pressure regulation and the development of novel antihypertensive agents.
• Renal Physiology Studies: Research into kidney function, sodium-potassium homeostasis, and diuretic pathways.
• Assay Development: Serves as a critical calibrant and control in the development of immunoassays (ELISA, RIA) for detecting related peptides.
• Drug Discovery Screening: Used in high-throughput screening (HTS) platforms to identify and validate new drug candidates targeting NPR pathways.
• Academic & Institutional Research: Fundamental research in endocrinology and molecular biology to elucidate peptide hormone signaling.

Basic Information

Product Name	(Tyr0)-Kaliuretic Peptide (Human)
CAS No.	309245-24-7
Molecular Formula	C119H190N38O34
Molecular Weight	2636.0 g/mol (approx.)
Synonyms	Tyr0-Kaliuretic Peptide; Tyr0-KP; Human Kaliuretic Peptide (Tyr0 analog); N-Tyrosylated Kaliuretic Peptide; Atrial Natriuretic Peptide-related peptide; ANP analog; urodilatin-related peptide; KP (1-32), Tyr0-
EINECS	Contact for details

Quality Control

Every batch of (Tyr0)-Kaliuretic Peptide (Human) is manufactured under strict quality systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) detailing results for HPLC purity, amino acid analysis, mass spectrometry (MS), and endotoxin levels. Our quality commitment supports research requiring high-purity, well-characterized bioactive peptides.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, consider aliquoting to minimize freeze-thaw cycles and maintain stability.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Amino Acid Composition	Within ±10% of theoretical
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Endotoxin	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.