Description

2-Phenylproline is a non-proteinogenic proline derivative featuring a phenyl substituent, which imparts unique conformational and steric properties. This compound is a valuable chiral building block and intermediate in advanced organic synthesis, particularly for the development of pharmaceuticals and bioactive molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors who require high-purity, specialized amino acid analogs for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of protease inhibitors, peptidomimetics, and other active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used as a building block for developing novel herbicides, fungicides, and plant growth regulators with enhanced activity.
• Peptide Chemistry: Incorporation into custom peptides to study structure-activity relationships (SAR) and to modulate peptide stability and bioavailability.
• Catalyst Ligand Synthesis: Serves as a precursor for chiral ligands used in asymmetric catalysis, such as in hydrogenation or cross-coupling reactions.
• Biochemical Research: Utilized as a tool compound in enzymatic studies and as a standard in analytical method development for amino acid analysis.
• Fine Chemical Production: An intermediate in the multi-step synthesis of complex organic molecules for specialty chemical applications.

Basic Information

Product Name	2-Phenylproline
CAS No.	308841-68-1
Molecular Formula	C₁₁H₁₃NO₂
Molecular Weight	191.23 g/mol
Synonyms	(2S)-2-Phenylpyrrolidine-2-carboxylic acid; L-2-Phenylproline; 2-Phenyl-L-proline; (S)-2-Phenylproline; 2-Phenylpyrrolidine-2-carboxylic acid; Proline, 2-phenyl-; (S)-2-Phenylpyrrolidine-2-carboxylic acid; 2-Phenyl-2-pyrrolidinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Phenylproline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.