Description

L-Norleucine, 4,4-Dimethyl- (9Ci) is a specialized, non-proteinogenic amino acid derivative characterized by its unique branched-chain structure. This compound is of significant value in advanced organic synthesis and pharmaceutical research, serving as a crucial chiral building block for the development of novel peptides and bioactive molecules. It is primarily utilized by research institutions, pharmaceutical development labs, and fine chemical manufacturers engaged in medicinal chemistry and proteomics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel peptide-based therapeutics and enzyme inhibitors.
• Biochemical Research: Used in proteomics and metabolic pathway studies as a non-natural amino acid analog to investigate protein structure and function.
• Organic Synthesis: Serves as a versatile building block for the synthesis of complex organic molecules, including custom peptides and macrocycles.
• Agrochemical Development: Potential application in the synthesis of specialized amino acid-derived compounds for crop protection research.
• Material Science: Can be incorporated into specialty polymers or coatings to modify material properties.

Basic Information

Product Name	L-Norleucine, 4,4-Dimethyl- (9Ci)
CAS No.	308807-04-7
Molecular Formula	C8H17NO2
Molecular Weight	159.23 g/mol
Synonyms	(2S)-2-Amino-4,4-dimethylhexanoic acid; L-4,4-Dimethylnorleucine; (S)-2-Amino-4,4-dimethylhexanoic acid; 4,4-Dimethyl-L-norleucine; L-2-Amino-4,4-dimethylhexanoic acid; 4,4-Dimethylnorleucine; (S)-4,4-Dimethylnorleucine; L-tert-Leucine homologue
EINECS	Contact for details

Quality Control

Our L-Norleucine, 4,4-Dimethyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the high standards required for research and synthesis applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specific characteristics.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-Isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.