Description

tert-Butyl (5-Bromo-2-(Methylthio)-6-oxopyrimidin-1-yl)acetate is a high-purity pyrimidine derivative building block, essential for advanced organic synthesis. Its value lies in its role as a versatile and reactive intermediate, enabling the construction of complex heterocyclic scaffolds. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in antiviral and anticancer research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides due to its reactive bromo and methylthio substituents.
• Material Science Research: Serves as a precursor for creating functionalized polymers or organic electronic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the discovery of new chemical entities.
• Custom Synthesis: Provides a critical starting point for custom manufacturing organizations (CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	tert-Butyl (5-Bromo-2-(Methylthio)-6-oxopyrimidin-1-yl)acetate
CAS No.	308276-66-6
Molecular Formula	C11H15BrN2O3S
Molecular Weight	335.22 g/mol
Synonyms	1-(2-tert-Butoxy-2-oxoethyl)-5-bromo-2-(methylthio)pyrimidin-6(1H)-one; 5-Bromo-2-(methylthio)-1-[(2-methyl-2-propanyl)oxy]-2-oxoethyl]-6(1H)-pyrimidinone; tert-Butyl 2-(5-bromo-2-(methylthio)-6-oxo-1,6-dihydropyrimidin-1-yl)acetate; 308276-66-6; Acetic acid, 2-[5-bromo-2-(methylthio)-6-oxo-1(6H)-pyrimidinyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl (5-Bromo-2-(Methylthio)-6-oxopyrimidin-1-yl)acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance in GMP-aligned synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the original container sealed under an inert atmosphere if possible.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.