Description

4-(2,6-Difluorophenoxy)Aniline is a high-purity aromatic amine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional structure, featuring both a reactive aniline group and a difluorophenoxy moiety, enabling the construction of complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators where the difluorophenoxy group enhances biological activity.
• Liquid Crystal & OLED Materials: Serves as a building block for electron-transport materials and charge-transport layers in electronic displays and devices.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart specific thermal, chemical, or optical properties.
• Dye & Pigment Manufacturing: Intermediate for producing high-performance, light-fast organic dyes and functional pigments.
• Research & Development: Valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	4-(2,6-Difluorophenoxy)Aniline
CAS No.	307308-81-2
Molecular Formula	C12H9F2NO
Molecular Weight	221.20 g/mol
Synonyms	Benzenamine, 4-(2,6-difluorophenoxy)-; 4-Amino-2',6'-difluorodiphenyl ether; 2,6-Difluorophenyl 4-aminophenyl ether; 4-(2,6-Difluorophenoxy)benzenamine; 4-Aminophenyl 2,6-difluorophenyl ether; Aniline, 4-(2,6-difluorophenoxy)-; 307308-81-2
EINECS	Contact for details

Quality Control

Our 4-(2,6-Difluorophenoxy)Aniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.