Description

4-(3-Fluorophenoxy)Aniline is a high-purity fluorinated aromatic amine building block of significant importance in advanced organic synthesis. Its unique structure, featuring both an aniline and a fluorinated phenoxy group, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by R&D and production chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in areas targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated diamines and other monomers used in high-performance electronic display materials.
• Polymer Modification: Employed to introduce aromatic amine functionality into polymer backbones, improving thermal stability and adhesion properties.
• Dye & Pigment Industry: Acts as an intermediate for synthesizing specialized fluorinated azo dyes and pigments with enhanced color fastness.
• Cross-coupling Reactions: A valuable substrate in Buchwald-Hartwig amination and other palladium-catalyzed coupling reactions to create complex biaryl ether structures.

Basic Information

Product Name	4-(3-Fluorophenoxy)Aniline
CAS No.	307308-62-9
Molecular Formula	C12H10FNO
Molecular Weight	203.21 g/mol
Synonyms	4-(3-Fluorophenoxy)benzenamine; 1-Amino-4-(3-fluorophenoxy)benzene; 3-Fluorophenyl 4-aminophenyl ether; 4-Amino-3'-fluorodiphenyl ether; Benzenamine, 4-(3-fluorophenoxy)-; 307308-62-9; 4-(3-Fluorophenoxy)phenylamine; 3-Fluoro-4-phenoxyaniline
EINECS	Contact for details

Quality Control

Our 4-(3-Fluorophenoxy)Aniline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements, supporting applications in cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent oxidation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.