Description

4-[Chloro(Difluoro)Methyl]-6-Methyl-2-Phenylpyrimidine is a high-purity, specialized pyrimidine derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated structure enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce chlorodifluoromethyl and phenylpyrimidine motifs into target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and production of novel drug candidates, particularly in kinase inhibitor and antiviral agent development.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides and herbicides, leveraging the pyrimidine core for biological activity.
• Material Science Research: Serves as a precursor for the synthesis of functionalized organic materials and ligands for metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and cellular processes.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	4-[Chloro(Difluoro)Methyl]-6-Methyl-2-Phenylpyrimidine
CAS No.	306979-31-7
Molecular Formula	C13H11ClF2N2
Molecular Weight	268.69 g/mol
Synonyms	4-(Chlorodifluoromethyl)-6-methyl-2-phenylpyrimidine; 2-Phenyl-4-(chlorodifluoromethyl)-6-methylpyrimidine; 4-(Chlorodifluoromethyl)-2-phenyl-6-methylpyrimidine; 6-Methyl-2-phenyl-4-(chlorodifluoromethyl)pyrimidine; 306979-31-7; 4-(Chloro(difluoro)methyl)-6-methyl-2-phenyl-pyrimidine
EINECS	Contact for details

Quality Control

Our 4-[Chloro(Difluoro)Methyl]-6-Methyl-2-Phenylpyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.