Description

Ethyl 2-[4-(Trifluoromethoxy)Anilino]Acetate is a high-purity organic intermediate featuring a trifluoromethoxy aniline core, a structure of significant interest in modern synthetic chemistry. This compound matters for its role as a critical building block in the development of advanced pharmaceuticals and agrochemicals, where the trifluoromethoxy group is prized for its ability to modulate lipophilicity and metabolic stability. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Serves as a vital building block for novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the anilinoacetate moiety.
• Ligand and Catalyst Development: Used in research for creating novel ligands and organocatalysts due to its electron-withdrawing trifluoromethoxy substituent.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology Probes: Acts as a starting material for synthesizing molecular probes used in biochemical and pharmacological research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	Ethyl 2-[4-(Trifluoromethoxy)Anilino]Acetate
CAS No.	306935-79-5
Molecular Formula	C11H12F3NO3
Molecular Weight	263.21 g/mol
Synonyms	Ethyl [4-(Trifluoromethoxy)phenylamino]acetate; Ethyl N-[4-(Trifluoromethoxy)phenyl]glycinate; 2-[[4-(Trifluoromethoxy)phenyl]amino]acetic acid ethyl ester; Acetic acid, 2-[[4-(trifluoromethoxy)phenyl]amino]-, ethyl ester; 4-(Trifluoromethoxy)anilinoacetic Acid Ethyl Ester; Ethyl (4-Trifluoromethoxyanilino)acetate; Ethyl 2-((4-(Trifluoromethoxy)phenyl)amino)acetate
EINECS	Contact for details

Quality Control

Our Ethyl 2-[4-(Trifluoromethoxy)Anilino]Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.