Description

6-Fluoro-4H-1,3-Benzodioxine-8-Carbaldehyde is a high-purity fluorinated benzodioxine derivative, serving as a critical advanced intermediate in modern organic synthesis. Its unique structure, featuring both a fluorine atom and a reactive aldehyde group, makes it a versatile building block for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, especially in medicinal chemistry programs targeting CNS disorders, anti-inflammatory agents, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and plant growth regulators, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring novel heterocyclic chemistry, fluorination reactions, and as a scaffold for library synthesis in high-throughput screening.
• Ligand and Catalyst Development: The aldehyde functionality allows for the creation of novel chiral ligands, catalysts, and metal-organic frameworks (MOFs) for asymmetric synthesis and catalysis.

Basic Information

Product Name	6-Fluoro-4H-1,3-Benzodioxine-8-Carbaldehyde
CAS No.	306934-87-2
Molecular Formula	C9H5FO3
Molecular Weight	180.13 g/mol
Synonyms	6-Fluoro-4H-1,3-benzodioxine-8-carboxaldehyde; 8-Formyl-6-fluoro-4H-1,3-benzodioxine; 6-Fluoro-1,3-benzodioxine-8-carbaldehyde; 306934-87-2; 6-Fluoro-4H-benzo[d][1,3]dioxine-8-carbaldehyde; 6-Fluoro-8-formyl-4H-1,3-benzodioxine
EINECS	Contact for details

Quality Control

Our 6-Fluoro-4H-1,3-Benzodioxine-8-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.