Description

1-(3-Methylphenyl)-4-(Pyrrolidin-1-Yl)-1H-Pyrazolo[3,4-D]Pyrimidine is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyrimidine class of heterocyclic compounds. This compound is of significant commercial interest for its role as a key building block in the synthesis of targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule drugs, particularly within oncology and kinase inhibitor research.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially kinase inhibitors.
• Biochemical Research: Used as a reference standard or a tool compound in enzymatic assays and biological pathway studies.
• Medicinal Chemistry R&D: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead molecules.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Academic Research: Utilized in university and institutional labs for investigating novel heterocyclic chemistry and its biological applications.

Basic Information

Product Name	1-(3-Methylphenyl)-4-(Pyrrolidin-1-Yl)-1H-Pyrazolo[3,4-D]Pyrimidine
CAS No.	305337-37-5
Molecular Formula	C₁₇H₁₉N₅
Molecular Weight	293.37 g/mol
Synonyms	4-(Pyrrolidin-1-yl)-1-(m-tolyl)-1H-pyrazolo[3,4-d]pyrimidine; 1-(3-Methylphenyl)-4-(1-pyrrolidinyl)-1H-pyrazolo[3,4-d]pyrimidine; 1-m-Tolyl-4-pyrrolidin-1-yl-1H-pyrazolo[3,4-d]pyrimidine; CAS 305337-37-5; Pyrazolo[3,4-d]pyrimidine derivative; m-Tolyl pyrazolopyrimidine intermediate
EINECS	Contact for details

Quality Control

Every batch of 1-(3-Methylphenyl)-4-(Pyrrolidin-1-Yl)-1H-Pyrazolo[3,4-D]Pyrimidine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.