Description

Ethyl 2-(Trifluoromethyl)Pyrimidine-5-Carboxylate is a high-value fluorinated pyrimidine building block essential for advanced organic synthesis. Its core value lies in the trifluoromethyl group, which imparts unique electronic and metabolic properties to target molecules, making it a critical intermediate for research and development. This compound is primarily needed by pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a building block for synthesizing specialty polymers, liquid crystals, and organic electronic materials requiring fluorinated aromatic systems.
• Chemical Research & Development: Employed in academic and industrial R&D labs for constructing complex heterocyclic compounds and exploring new reaction methodologies.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and contract manufacturing organizations (CMOs) serving the life sciences sector.

Basic Information

Product Name	Ethyl 2-(Trifluoromethyl)Pyrimidine-5-Carboxylate
CAS No.	304693-64-9
Molecular Formula	C8H7F3N2O2
Molecular Weight	220.15 g/mol
Synonyms	5-Pyrimidinecarboxylic acid, 2-(trifluoromethyl)-, ethyl ester; Ethyl 2-(trifluoromethyl)-5-pyrimidinecarboxylate; 2-Trifluoromethyl-pyrimidine-5-carboxylic acid ethyl ester; Ethyl 2-(trifluoromethyl)pyrimidine-5-carboxylate; 304693-64-9; Ethyl α,α,α-trifluoro-2-pyrimidinecarboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-(Trifluoromethyl)Pyrimidine-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.