Description

3-Bromo-5-Phenyl-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for research and development in pharmaceutical and agrochemical discovery, where its unique pyrazolopyrimidine core enables the creation of novel bioactive molecules. It is primarily sought after by medicinal chemists and process development scientists working on kinase inhibitors, antiviral agents, and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors and other small-molecule drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating novel active ingredients with potential herbicidal or fungicidal properties.
• Chemical Biology Probes: Employed in the development of molecular probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a component for advanced organic electronic materials due to its fused heterocyclic structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and non-commercial research quantities.

Basic Information

Product Name	3-Bromo-5-Phenyl-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid
CAS No.	304687-28-3
Molecular Formula	C₁₄H₇BrF₃N₃O₂
Molecular Weight	386.13 g/mol
Synonyms	3-Bromo-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid; 304687-28-3; 3-Bromo-5-phenyl-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinecarboxylic acid; Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid, 3-bromo-5-phenyl-7-(trifluoromethyl)-; 3-Bromo-5-phenyl-7-trifluoromethylpyrazolo[1,5-a]pyrimidine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-Phenyl-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.