Description

n-Hydroxy-2,5-Bis(2,2,2-Trifluoroethoxy)Benzenecarboxamide is a specialized fluorinated aromatic compound, serving as a high-value intermediate in advanced organic synthesis. Its molecular structure, featuring a hydroxamic acid moiety and trifluoroethoxy substituents, makes it a critical building block for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of targeted bioactive molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition.
• Agrochemical Research: Building block for developing advanced herbicides, fungicides, and pesticides with enhanced efficacy and environmental profiles.
• Chemical Synthesis: Versatile reagent for introducing the N-hydroxycarboxamide and trifluoroethoxy functional groups into complex molecular architectures.
• Material Science: Potential monomer or additive for creating specialty polymers with unique surface properties or chemical resistance.
• Biochemical Probes: Used in research to develop inhibitors and probes for metalloenzymes, such as histone deacetylases (HDACs).

Basic Information

Item	Detail
Product Name	n-Hydroxy-2,5-Bis(2,2,2-Trifluoroethoxy)Benzenecarboxamide
CAS No.	303996-38-5
Molecular Formula	C11H9F6NO4
Molecular Weight	333.19 g/mol
Synonyms	2,5-Bis(2,2,2-trifluoroethoxy)-N-hydroxybenzamide; N-Hydroxy-2,5-bis(2,2,2-trifluoroethoxy)benzamide; 2,5-Bis(2,2,2-trifluoroethoxy)benzhydroxamic acid; SAHA Derivative; Trifluoroethoxy Hydroxamic Acid; TFE-HA; Benzamide, N-hydroxy-2,5-bis(2,2,2-trifluoroethoxy)-; HDAC Inhibitor Intermediate
EINECS	Contact for details

Quality Control

Our n-Hydroxy-2,5-Bis(2,2,2-Trifluoroethoxy)Benzenecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality parameters. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.