Description

1-(4-[3-(4-Chlorophenyl)Pyrazolo[1,5-A]Pyrimidin-7-Yl]Phenyl)-3,3-Dimethyl-2-Azetanone is a high-value, complex heterocyclic compound featuring a pyrazolo[1,5-a]pyrimidine core, a key structural motif in medicinal chemistry. This compound serves as a critical advanced pharmaceutical intermediate for the research and development of novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of targeted small molecule drugs.

Application

This specialized intermediate is designed for sophisticated chemical synthesis in regulated industries. Its primary applications include:

• Pharmaceutical Intermediate: Serving as a key building block in the synthesis of potential drug candidates targeting various disease pathways.
• Kinase Inhibitor Research: Used in the development of novel kinase inhibitors due to the privileged pyrazolopyrimidine scaffold.
• Chemical Biology Probes: Acting as a core structure for creating molecular probes to study biological processes and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic & Institutional Research: Utilized in university and research institute laboratories for exploratory medicinal chemistry programs.

Basic Information

Product Name	1-(4-[3-(4-Chlorophenyl)Pyrazolo[1,5-A]Pyrimidin-7-Yl]Phenyl)-3,3-Dimethyl-2-Azetanone
CAS No.	303985-95-7
Molecular Formula	C23H19ClN4O
Molecular Weight	402.88 g/mol
Synonyms	1-(4-(3-(4-Chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl)phenyl)-3,3-dimethylazetidin-2-one; 3,3-Dimethyl-1-[4-[3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]azetidin-2-one; Azetidin-2-one, 1-[4-[3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3,3-dimethyl-; CAS 303985-95-7; 7-[4-(3,3-Dimethyl-2-oxo-1-azetidinyl)phenyl]-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidine
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and MS to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring full traceability and compliance with your research or cGMP-grade requirements. We support custom synthesis with tailored purity specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). For long-term storage, consider using inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0% (Standard Grade)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.