Description

8-Amino-7-(2-Chlorobenzyl)-3-Methyl-3,7-Dihydro-1H-Purine-2,6-Dione is a high-purity, specialized purine derivative with significant potential in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate for creating novel therapeutic agents, particularly in oncology and immunology. It is essential for research chemists and process development scientists in pharmaceutical companies and contract research organizations (CROs) focused on developing next-generation small molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel purine-based drug candidates targeting various disease pathways.
• Oncology Research: Used in the development of potential kinase inhibitors and other targeted cancer therapies.
• Immunomodulator Synthesis: Serves as a precursor for compounds being investigated for autoimmune and inflammatory disorders.
• Chemical Biology: Employed as a probe or tool compound in biochemical assays to study enzyme function and signal transduction.
• Process Chemistry: Utilized in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	8-Amino-7-(2-Chlorobenzyl)-3-Methyl-3,7-Dihydro-1H-Purine-2,6-Dione
CAS No.	303973-72-0
Molecular Formula	C₁₃H₁₂ClN₅O₂
Molecular Weight	305.72 g/mol
Synonyms	8-Amino-7-[(2-chlorophenyl)methyl]-3-methyl-3,7-dihydro-1H-purine-2,6-dione; 8-Amino-7-(2-chlorobenzyl)-3-methylxanthine; 8-Amino-7-(2-chlorobenzyl)-3-methyl-1H-purine-2,6(3H,7H)-dione; 303973-72-0; 2,6-Dioxo-8-amino-7-(2-chlorobenzyl)-3-methyl-1,2,3,6,7,8-hexahydropurine; 7-(2-Chlorobenzyl)-8-amino-3-methyl-3,7-dihydro-1H-purine-2,6-dione
EINECS	Contact for details

Quality Control

Our 8-Amino-7-(2-Chlorobenzyl)-3-Methyl-3,7-Dihydro-1H-Purine-2,6-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.