Description

7-Ethyl-8-(Isobutylthio)-3-Methyl-3,7-Dihydro-1H-Purine-2,6-Dione is a high-purity, synthetic purine derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical chemical intermediate or pharmacological reference standard for the synthesis and study of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new drug candidates, particularly those targeting neurological or metabolic pathways.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel purine-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference compound or substrate in enzymatic studies and receptor binding assays to investigate purinergic signaling pathways.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of new drug candidates.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in HPLC or LC-MS analysis of related compounds.
• Preclinical Development: Utilized in the early-stage development of potential therapeutics for conditions like inflammation, ischemia, or cognitive disorders.
• Fine Chemical Synthesis: An advanced intermediate for custom synthesis and contract manufacturing of specialized, low-volume chemical entities.

Basic Information

Item	Details
Product Name	7-Ethyl-8-(Isobutylthio)-3-Methyl-3,7-Dihydro-1H-Purine-2,6-Dione
CAS No.	303971-00-8
Molecular Formula	C₁₂H₁₈N₄O₂S
Molecular Weight	282.36 g/mol
Synonyms	8-(2-Methylpropylthio)-3,7-dimethyl-7H-purine-2,6-dione; 7-Ethyl-8-(isobutylthio)-3-methyl-3,7-dihydro-1H-purine-2,6-dione; 3-Methyl-7-ethyl-8-(isobutylthio)-3,7-dihydro-1H-purine-2,6-dione; Isobutylthiotheophylline derivative; 8-(Isobutylthio)-3,7-dimethylxanthine; 7-Ethyl-8-(2-methylpropylthio)-3-methylxanthine
EINECS	Contact for details

Quality Control

Our 7-Ethyl-8-(Isobutylthio)-3-Methyl-3,7-Dihydro-1H-Purine-2,6-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC purity assay, identity confirmation (IR, NMR), and residual solvent analysis, to ensure it meets stringent specifications for research and development use. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.