Description

8-Bromo-7-(2-Hydroxy-3-(o-Tolyloxy)Propyl)-3-Methyl-3,7-Dihydro-1H-Purine-2,6-Dione is a high-purity, advanced pharmaceutical intermediate of significant interest in modern medicinal chemistry. This compound matters for its role as a key synthetic precursor in the development of novel therapeutic agents, particularly those targeting adenosine receptor pathways. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material for the synthesis of potential drug candidates, where its structural complexity enables the exploration of new bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel xanthine derivatives and adenosine receptor antagonists for preclinical research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new compounds with potential neurological or cardiovascular activity.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the multi-step synthesis of complex, high-value target molecules for new drug applications.
• Biochemical Tool Compound: Employed in academic and industrial laboratories to study purinergic signaling pathways and receptor interactions.
• Process Chemistry & Scale-Up: Utilized in optimizing synthetic routes from milligram to kilogram scale for clinical trial material production.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting the pharmaceutical industry's drug discovery and development pipelines.

Basic Information

Product Name	8-Bromo-7-(2-Hydroxy-3-(o-Tolyloxy)Propyl)-3-Methyl-3,7-Dihydro-1H-Purine-2,6-Dione
CAS No.	303970-66-3
Molecular Formula	C₁₆H₁₇BrN₄O₄
Molecular Weight	409.24 g/mol
Synonyms	8-Bromo-7-[2-hydroxy-3-(2-methylphenoxy)propyl]-3-methyl-3,7-dihydro-1H-purine-2,6-dione; 8-Bromo-7-(2-hydroxy-3-(o-tolyloxy)propyl)-3-methylxanthine; 8-Bromo-7-(2-hydroxy-3-(2-methylphenoxy)propyl)-3-methylxanthine; 303970-66-3; Xanthine derivative, 8-bromo-7-(2-hydroxy-3-(o-tolyloxy)propyl)-3-methyl-; 1H-Purine-2,6-dione, 8-bromo-7-[2-hydroxy-3-(2-methylphenoxy)propyl]-3-methyl-3,7-dihydro-
EINECS	Contact for details

Quality Control

Our 8-Bromo-7-(2-Hydroxy-3-(o-Tolyloxy)Propyl)-3-Methyl-3,7-Dihydro-1H-Purine-2,6-Dione is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Products undergo rigorous quality testing including HPLC, NMR, and MS to verify identity and purity, ensuring compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.