Description

8-((2-Hydroxyethyl)Thio)-3-Methyl-7-(4-Methylbenzyl)-3,7-Dihydro-1H-Purine-2,6-Dione is a high-purity, synthetically derived xanthine derivative with a unique thioether side chain. This compound is valued as a key pharmaceutical intermediate and research chemical for developing novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of advanced drug candidates.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel adenosine receptor antagonists and other purine-based drug candidates.
• Biochemical Research: Used as a reference standard and active compound in studies targeting neurological and cardiovascular pathways.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses requiring a functionalized purine derivative with specific solubility and reactivity profiles.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of clinical trial materials.

Basic Information

Product Name	8-((2-Hydroxyethyl)Thio)-3-Methyl-7-(4-Methylbenzyl)-3,7-Dihydro-1H-Purine-2,6-Dione
CAS No.	303970-01-6
Molecular Formula	C₁₆H₁₈N₄O₃S
Molecular Weight	346.41 g/mol
Synonyms	8-[(2-Hydroxyethyl)sulfanyl]-3-methyl-7-[(4-methylphenyl)methyl]-1H-purine-2,6-dione; 8-(2-Hydroxyethylthio)-3-methyl-7-(4-methylbenzyl)-3,7-dihydro-1H-purine-2,6-dione; 8-(2-Hydroxyethylthio)-3-methyl-7-(p-methylbenzyl)xanthine; 8-Hydroxyethylthio-3-methyl-7-(4-methylbenzyl)xanthine; 303970-01-6; Xanthine derivative, 8-(2-hydroxyethylthio)-3-methyl-7-(4-methylbenzyl)-
EINECS	Contact for details

Quality Control

Our production of 8-((2-Hydroxyethyl)Thio)-3-Methyl-7-(4-Methylbenzyl)-3,7-Dihydro-1H-Purine-2,6-Dione adheres to stringent quality protocols suitable for pharmaceutical research. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.