Description

n-Methyl-Dl-Aspartic Acid Monohydrate is a modified amino acid derivative, serving as a crucial building block and chiral synthon in advanced organic synthesis. This compound is valued for its role in the research and development of novel pharmaceuticals, peptides, and biochemical probes. It is primarily utilized by R&D laboratories, pharmaceutical companies, and fine chemical manufacturers focused on neuroscience, metabolic studies, and peptidomimetic drug discovery.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of NMDA receptor antagonists and other neuroactive compounds.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to amino acid metabolism.
• Peptide Synthesis: Serves as a non-proteinogenic amino acid building block for creating modified peptides with altered properties.
• Chiral Resolution Studies: Employed in methodological development for separating enantiomers due to its DL-mixture form.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.
• Academic Research: Fundamental research tool in organic chemistry and medicinal chemistry departments for exploring new synthetic pathways.

Basic Information

Product Name	n-Methyl-Dl-Aspartic Acid Monohydrate
CAS No.	303750-06-3
Molecular Formula	C5H9NO5 • H2O
Molecular Weight	179.14 g/mol (Anhydrous basis: 161.13 g/mol)
Synonyms	DL-N-Methylaspartic Acid Monohydrate; 2-(Methylamino)succinic Acid Monohydrate; N-Methyl-DL-aspartic Acid Hydrate; Methylaminosuccinic Acid Monohydrate; (±)-N-Methylaspartic Acid Monohydrate; NMDA (common abbreviation context); Aspartic Acid, N-methyl-, DL-, monohydrate
EINECS	Contact for details

Quality Control

Our n-Methyl-Dl-Aspartic Acid Monohydrate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-purity research-grade standards. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	Theoretical (Monohydrate)
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Optical Rotation	± 0.5° (c=1 in H2O)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.