Description

Ethyl 2-([6-[(Phenylsulfonyl)Methyl]-2-(4-Pyridinyl)-4-Pyrimidinyl]Sulfanyl)Acetate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure incorporating pyrimidine, pyridine, and sulfonyl functional groups. This compound is of significant value for research and development in medicinal chemistry, serving as a critical building block for the synthesis of novel therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing targeted small molecule drugs, particularly in oncology and antiviral fields.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Kinase Inhibitor Development: Serves as a core scaffold or a functionalized fragment for designing protein kinase inhibitors due to its pyrimidine-pyridine motif.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function and cellular signaling processes.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic projects.
• Academic Research: Used in university and institutional labs for exploratory synthetic chemistry and bioorganic research projects.

Basic Information

Product Name	Ethyl 2-([6-[(Phenylsulfonyl)Methyl]-2-(4-Pyridinyl)-4-Pyrimidinyl]Sulfanyl)Acetate
CAS No.	303147-07-1
Molecular Formula	C20H19N3O4S2
Molecular Weight	429.51 g/mol
Synonyms	Ethyl 2-((6-((Phenylsulfonyl)methyl)-2-(pyridin-4-yl)pyrimidin-4-yl)thio)acetate; 2-((6-((Phenylsulfonyl)methyl)-2-(4-pyridinyl)-4-pyrimidinyl)thio)acetic acid ethyl ester; Acetic acid, 2-[[6-[(phenylsulfonyl)methyl]-2-(4-pyridinyl)-4-pyrimidinyl]thio]-, ethyl ester; CAS 303147-07-1; 303147-07-1; Ethyl 2-((6-((phenylsulfonyl)methyl)-2-(4-pyridyl)pyrimidin-4-yl)sulfanyl)acetate
EINECS	Contact for details

Quality Control

Our production of Ethyl 2-([6-[(Phenylsulfonyl)Methyl]-2-(4-Pyridinyl)-4-Pyrimidinyl]Sulfanyl)Acetate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research applications. All material is characterized and released with a comprehensive Certificate of Analysis (COA). Our quality systems are designed to support cGMP compliance for advanced intermediates, and we can provide material suitable for use in regulated pre-clinical and early-phase development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider inert atmosphere packaging to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single unknown impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.