Description

1-(2-Pyrimidinyl)Piperidine-4-Carboxylic Acid CAS NO 303144-44-7 is a high-purity heterocyclic building block featuring a piperidine core substituted with both a carboxylic acid and a pyrimidinyl group. This unique bifunctional structure makes it a critical intermediate for the synthesis of complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients, particularly in the areas of medicinal chemistry and crop protection.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor research and central nervous system (CNS) targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its heterocyclic scaffold for bioactivity.
• Chemical Biology & Proteomics: Serves as a versatile scaffold or linker in the design of chemical probes and molecular tools for studying biological systems.
• Material Science Research: Potential precursor for specialty polymers or ligands in catalytic systems due to its chelating carboxylic acid group and aromatic nitrogen heterocycle.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	1-(2-Pyrimidinyl)Piperidine-4-Carboxylic Acid
CAS No.	303144-44-7
Molecular Formula	C10H13N3O2
Molecular Weight	207.23 g/mol
Synonyms	4-Piperidinecarboxylic acid, 1-(2-pyrimidinyl)-; 1-(Pyrimidin-2-yl)piperidine-4-carboxylic acid; 1-(2-Pyrimidinyl)-4-piperidinecarboxylic acid; Piperidine-4-carboxylic acid, 1-(2-pyrimidinyl)-; 303144-44-7; 1-Pyrimidin-2-ylpiperidine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 1-(2-Pyrimidinyl)Piperidine-4-Carboxylic Acid is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.