Description

8,8-Dimethyl-2-thioxo-1,2,3,6,8,9-hexahydro-4H-pyrano[3',4':5,6]pyrido[2,3-d]pyrimidin-4-one is a sophisticated heterocyclic compound belonging to the pyranopyridopyrimidinone class, serving as a critical advanced intermediate in modern organic synthesis. Its complex fused-ring structure makes it a valuable scaffold for pharmaceutical research and development, particularly in the discovery of novel bioactive molecules. This high-purity building block is essential for medicinal chemists and R&D laboratories in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents or functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting various diseases.
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Serves as an intermediate in the research of new pesticides or herbicides with novel modes of action.
• Chemical Biology Probe Synthesis: Utilized for creating molecular probes to study biological pathways and protein functions.
• Organic Electronic Material Precursor: Investigated as a building block for π-conjugated systems in materials science applications.
• Academic & Institutional R&D: Employed in universities and research institutes for fundamental studies in heterocyclic chemistry and reaction methodology development.

Basic Information

Product Name	8,8-Dimethyl-2-thioxo-1,2,3,6,8,9-hexahydro-4H-pyrano[3',4':5,6]pyrido[2,3-d]pyrimidin-4-one
CAS No.	303051-81-2
Molecular Formula	C₁₃H₁₅N₃O₂S
Molecular Weight	277.34 g/mol
Synonyms	8,8-Dimethyl-2-thioxo-1,2,3,6,8,9-hexahydro-4H-pyrano[3',4':5,6]pyrido[2,3-d]pyrimidin-4-one; 4H-Pyrano[3',4':5,6]pyrido[2,3-d]pyrimidin-4-one, 1,2,3,6,8,9-hexahydro-8,8-dimethyl-2-thioxo-; 303051-81-2; Pyrano[3',4':5,6]pyrido[2,3-d]pyrimidine derivative; CAS 303051-81-2
EINECS	Contact for details

Quality Control

Our 8,8-Dimethyl-2-thioxo-1,2,3,6,8,9-hexahydro-4H-pyrano[3',4':5,6]pyrido[2,3-d]pyrimidin-4-one is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support custom synthesis and can tailor purity grades to meet specific project requirements, from laboratory research to pre-clinical development scales.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.