Description

2,5-Anhydro-3-Deoxy-3-(3,4-Dihydro-2,4-Dioxo-1(2H)-Pyrimidinyl)-D-Mannitol is a high-purity, specialized nucleoside analog building block of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of novel antiviral and anticancer agents, offering researchers a precise tool for structure-activity relationship (SAR) studies. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on nucleoside chemistry and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel nucleoside-based antiviral and anticancer therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the biological activity and pharmacokinetic properties of new drug candidates.
• Biochemical Probe Development: Serves as a building block for creating labeled or modified nucleosides used to study enzyme mechanisms and biological pathways.
• Antiviral Agent Synthesis: Specifically employed in the research and synthesis of potential agents targeting viral polymerases and reverse transcriptases.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for fundamental studies in organic synthesis and bioorganic chemistry.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	2,5-Anhydro-3-Deoxy-3-(3,4-Dihydro-2,4-Dioxo-1(2H)-Pyrimidinyl)-D-Mannitol
CAS No.	302790-82-5
Molecular Formula	C10H12N2O7
Molecular Weight	272.21 g/mol
Synonyms	3-(2,4-Dioxo-3,4-dihydro-1(2H)-pyrimidinyl)-2,5-anhydro-3-deoxy-D-mannitol; 1-(2,5-Anhydro-3-deoxy-D-mannitol-3-yl)uracil; 3-(2,4-Dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-2,5-anhydro-3-deoxy-D-mannitol; D-Mannitol, 2,5-anhydro-3-deoxy-3-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-, (3R)-; Uracil, 1-(2,5-anhydro-3-deoxy-D-mannitol-3-yl)-; Nucleoside analog intermediate; Anhydro-deoxy-mannitol uracil derivative
EINECS	Contact for details

Quality Control

Our 2,5-Anhydro-3-Deoxy-3-(3,4-Dihydro-2,4-Dioxo-1(2H)-Pyrimidinyl)-D-Mannitol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.