Description

n-(4-Fluorophenyl)-2-((5,6,7,8-Tetrahydrobenzo[4,5]Thieno[2,3-D]Pyrimidin-4-Yl)Thio)Acetamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly for its role as a key building block in the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Kinase Inhibitor Development: Used as a core scaffold or building block for creating potent and selective kinase inhibitors due to its fused thienopyrimidine structure.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize drug-like properties and biological activity.
• Biochemical Tool Compound: Can be utilized in vitro to study specific biological pathways and enzyme interactions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.
• Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	n-(4-Fluorophenyl)-2-((5,6,7,8-Tetrahydrobenzo[4,5]Thieno[2,3-D]Pyrimidin-4-Yl)Thio)Acetamide
CAS No.	302575-78-6
Molecular Formula	C20H18FN3OS2
Molecular Weight	399.50 g/mol
Synonyms	4-(((2-((4-Fluorophenyl)amino)-2-oxoethyl)thio)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine; N-(4-Fluorophenyl)-2-((5,6,7,8-tetrahydro-4H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-yl)thio)acetamide; 302575-78-6; 4H-Cyclohepta[4,5]thieno[2,3-d]pyrimidine, N-(4-fluorophenyl)-2-((5,6,7,8-tetrahydro-4H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-yl)thio)acetamide; Acetamide, N-(4-fluorophenyl)-2-((5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-yl)thio)-
EINECS	Contact for details

Quality Control

Our n-(4-Fluorophenyl)-2-((5,6,7,8-Tetrahydrobenzo[4,5]Thieno[2,3-D]Pyrimidin-4-Yl)Thio)Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and compliance data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.