Description

Compstatin Control Peptide is a synthetic peptide analog specifically designed as a critical reference standard for research involving the complement C3 inhibitor, Compstatin. This compound is essential for validating experimental results, ensuring assay specificity, and controlling for non-specific effects in complement system studies. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, biotechnology, and academic sectors focused on immunology, inflammatory diseases, and drug discovery.

Application

• Biomedical Research Control: Serves as a negative or reference control in studies investigating the activity and mechanism of Compstatin and its derivatives.
• Assay Validation: Critical for the development and validation of biochemical and cell-based assays targeting the complement C3 protein.
• Drug Discovery & Development: Used in high-throughput screening (HTS) campaigns and lead optimization processes to identify and characterize novel complement inhibitors.
• Quality Control Standard: Employed in QC laboratories to benchmark the purity and performance of active Compstatin batches in pharmaceutical manufacturing.
• Academic Research: Supports fundamental research in immunology, studying the role of the complement system in disease models.
• Diagnostic Development: Acts as a key component in developing diagnostic kits for complement pathway analysis.

Basic Information

Product Name	Compstatin Control Peptide
CAS No.	301544-78-5
Molecular Formula	C78H111N19O26
Molecular Weight	1690.9 g/mol
Synonyms	Compstatin Inactive Control; Compstatin Negative Control Peptide; Ac-Ile-[Cys-Val-Trp(Me)-Gln-Asp-Trp-Sar-Ala-His-Arg-Cys]-mIle-NH2 (Disulfide bridge); Complement C3 Inhibitor Control; Cyclic Peptide Control; 13-mer Cyclic Peptide Control; Ac-ICVVQDWSAHRC-mIle-NH2 (Disulfide bridge: 2-12)
EINECS	Contact for details

Quality Control

Our Compstatin Control Peptide is manufactured under stringent conditions to ensure the highest standards of purity and consistency, suitable for critical research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to GMP principles for peptide synthesis, and our quality system is designed to meet the rigorous demands of pharmaceutical R&D and commercial manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum conforms to theoretical molecular weight
Purity (HPLC)	≥ 95%
Assay (HPLC)	≥ 98% on anhydrous basis
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.