Description

n-Butyl-5,6,7,8-Tetrahydrobenzo[4,5]Thieno[2,3-D]Pyrimidin-4-Amine is a high-purity, advanced pharmaceutical intermediate belonging to the fused heterocyclic compound class. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for targeted therapies.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted small-molecule therapeutics.
• Organic Synthesis Building Block: Used in research-scale and pilot-scale organic chemistry for constructing complex fused-ring systems with potential biological activity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize pharmacological properties of lead compounds.
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to commercial manufacturing for new chemical entities (NCEs).
• Biochemical Research: May be used as a tool compound or ligand in biochemical assays to study specific enzyme or receptor interactions.

Basic Information

Product Name	n-Butyl-5,6,7,8-Tetrahydrobenzo[4,5]Thieno[2,3-D]Pyrimidin-4-Amine
CAS No.	300815-16-1
Molecular Formula	C16H21N3S
Molecular Weight	287.43 g/mol
Synonyms	4-(Butylamino)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine; 4-Amino-N-butyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine; 300815-16-1; BTHTP; n-Butylamino-tetrahydrobenzothienopyrimidine; Tetrahydrobenzothieno[2,3-d]pyrimidin-4-amine, N-butyl-; Butyl-tetrahydrobenzothienopyrimidinamine
EINECS	Contact for details

Quality Control

Our n-Butyl-5,6,7,8-Tetrahydrobenzo[4,5]Thieno[2,3-D]Pyrimidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.