Description

6-Bromo-Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its brominated pyrazolopyrimidine core. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel, targeted therapeutic agents. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitor candidates targeting oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities with enhanced potency and selectivity.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study enzyme function and cellular signaling pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Agrochemical Research: Potential application as an intermediate in the development of new crop protection agents.

Basic Information

Product Name	6-Bromo-Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid
CAS No.	300717-72-0
Molecular Formula	C7H4BrN3O2
Molecular Weight	242.03 g/mol
Synonyms	6-Bromo-2-pyrazolo[1,5-a]pyrimidinecarboxylic acid; 6-Bromo-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid; 6-Bromopyrazolo[1,5-a]pyrimidine-2-carboxylic acid; 300717-72-0; 6-Bromo-1H-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid; 6-Bromo-7-azaindole-2-carboxylic acid (common name); 6-Bromo-2-carboxypyrazolo[1,5-a]pyrimidine
EINECS	Contact for details

Quality Control

Our 6-Bromo-Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high-purity standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.