Description

2-Chloro-3-Trifluoromethylbenzylamine.Hcl is a high-purity, halogenated benzylamine derivative, specifically the hydrochloride salt form. This compound serves as a critical pharmaceutical intermediate and versatile building block in advanced organic synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for enhanced biological activity and stability.
• Ligand and Catalyst Development: Serves as a valuable starting material for creating novel ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with specific electronic or structural properties.
• Chemical Biology Probes: Acts as a building block for developing molecular probes and diagnostic agents in biochemical research.

Basic Information

Product Name	2-Chloro-3-Trifluoromethylbenzylamine.Hcl
CAS No.	39959-48-3
Molecular Formula	C8H8ClF3N•HCl
Molecular Weight	250.51 g/mol
Synonyms	2-Chloro-3-(trifluoromethyl)benzylamine hydrochloride; 1-(2-Chloro-3-(trifluoromethyl)phenyl)methanamine hydrochloride; α-Amino-2-chloro-α,α,α-trifluoro-m-xylene hydrochloride; (2-Chloro-3-trifluoromethylbenzyl)amine hydrochloride; Benzenemethanamine, 2-chloro-α,α,α-trifluoro-, hydrochloride; 2-Chloro-α,α,α-trifluoro-m-toluidine hydrochloride (related amine form)
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-3-Trifluoromethylbenzylamine.Hcl adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets exacting customer specifications. Certificates of Analysis (COA) with complete batch data are provided to guarantee traceability, consistency, and compliance with relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.