Description

3-Methoxy-O,α-Dimethyl-L-Tyrosine is a specialized, non-proteinogenic amino acid derivative of L-tyrosine. This compound is a key chiral building block and intermediate in the synthesis of complex pharmaceutical molecules, particularly those targeting neurological and cardiovascular systems. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of advanced drug candidates, especially in neurology and cardiology.
• Biochemical Research: Used as a precursor or reference standard in metabolic pathway studies and enzyme inhibition research.
• Peptide Chemistry: Serves as a modified tyrosine analog for the design and synthesis of novel peptide-based therapeutics.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in stereoselective chemical reactions to introduce specific chiral centers.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical analysis.

Basic Information

Product Name	3-Methoxy-O,α-Dimethyl-L-Tyrosine
CAS No.	39948-18-0
Molecular Formula	C₁₂H₁₇NO₄
Molecular Weight	239.27 g/mol
Synonyms	O-Methyl-3-O-methyl-L-tyrosine; α-Methyl-3-methoxy-L-tyrosine; (2S)-2-Amino-3-(4-hydroxy-3-methoxyphenyl)-2-methylpropanoic acid; L-α-Methyl-3-methoxytyrosine; MDL 72394; 3-Methoxy-α-methyl-L-tyrosine; 3-OMe-α-Me-L-Tyr
EINECS	Contact for details

Quality Control

Our 3-Methoxy-O,α-Dimethyl-L-Tyrosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.